中日精品无码一本二本三本_久久久久久精品免费_国产SUV精品一区二区,99久久久国产精品免费蜜臀,麻豆国产VA免费精品高清在线,国产精品嫩草影院永久…,久久精品国产99久久无毒不卡,国产精品亚洲成在人线_国产精品亚亚洲欧关中字幕_久久久久久精品免费免费99久久国产综合_国产伦精品一区二区三区视频猫咪_国产片婬乱一级毛片调教视频_中日精品无码一本二本三本

加入收藏 | 設(shè)為首頁 | 聯(lián)系我們

產(chǎn)品搜索

產(chǎn)品分類

聯(lián)系我們

聯(lián)系人：蔣經(jīng)理
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com

產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73229CSF1R（CSF1 Dependent）/BaF3

CSF1R（CSF1 Dependent）/BaF3
名稱 CSF1R（CSF1 Dependent）/BaF3
型號 CBP73229
報價
特點(diǎn) CSF1R（CSF1 Dependent）/BaF3,母細(xì)胞：BaF3
  • 詳細(xì)內(nèi)容
CBP73229
I. Introduction

Cell Line Name：

CSF1R(CSF1 Dependent)/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Monitor the CSF1R/MAPK/ERK signaling pathway activity and SRF-mediated activity. Screen for activators or inhibitors of the CSF1R/MAPK/ERK signaling pathway.

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS+0.1ug/ml M-CSF

Mycoplasma Status:

Negative

II.Background

CSF1R is activated by either of two cytokines, CSF1 (MCSF; CSF-1) and IL-34 (IL34), causing homodimerization and activation of downstream kinase activity. CSF1R is expressed on the surface of monocytes and macrophages, and its activation controls the growth, function, and differentiation of macrophages. This interaction is used by numerous cancer types, such as diffuse-type tenosynovial giant cell tumors (dt-GCT), to evade the immune system. By overexpressing the cytokine CSF1, these cells drive the development and survival of Tumor-Associated Macrophages (TAMs), which in turn suppress the local immune response to the cancer.

III. Representative Data

1.Anti-proliferation assay


CBP73229 改.jpg

Figure 2. Anti-proliferation assay of two reference compounds on the CSF1R(CSF1 Dependent)/BaF3 Stable Cell Line.





如果你對CBP73229CSF1R（CSF1 Dependent）/BaF3感興趣，想了解更詳細(xì)的產(chǎn)品信息服務體系，填寫下表直接與廠家聯(lián)系：


留言框

  • 產(chǎn)品：

  • 您的單位：

  • 您的姓名：

  • 聯(lián)系電話：

  • 常用郵箱：

  • 省份：

  • 詳細(xì)地址：

  • 補(bǔ)充說明：

  • 驗(yàn)證碼：

    請輸入計(jì)算結(jié)果（填寫阿拉伯?dāng)?shù)字），如：三加四=7

化工儀器網(wǎng)

推薦收藏該企業(yè)網(wǎng)站