名稱 | PIK3CA p.E545K Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10322 |
報(bào)價(jià) | ![]() |
特點(diǎn) | PIK3CA p.E545K Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10322PIK3CA p.E545K Reference Standard 標(biāo)準(zhǔn)品

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CBP10322 | |
Format | Genomic DNA |
Description | PIK3CA E545K is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545K results in increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and is transforming in culture (PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.1633G>A |
AA Change | p.E545K |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_006218.1 |
Cosmic ID | COSM763 |
Chr position(GRCh37) | chr3:178936091 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |